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6 April 2011 - Stephen Friend has been recognized with an Ashoka Fellowship for his work promoting both social and technical transformations in the way genomics research contributes to healthcare. Ashoka is a global organization supporting community leaders who share qualities traditionally associated with leading business entrepreneurs – vision, innovation, determination and long-term commitment – but are committed to systemic social change in their fields.  This is especially noteworthy because the majority of Fellows work in areas such as human rights, the environment and social services.  Stephen's selection is a great recognition that Sage Bionetworks was created to do much more than advance medical technology and highlights our mission to change the cultural framework in which researchers and the public operate.  Press Release.

31 March 2011- The Precompetitive Space: Time to Move the Yardstick.Thea Norman, Aled Edwards, Chas Bountra, and Stephen Friend have published a commentary on the workshop they organized in February to explore alternatives to the current drug discovery paradigm. It reviews the context and the the opportunity for a new public-private partnership establishing a pre-competitive archipelago of stakeholders to achieve proof of clinical mechanism (POCM) for selected disease targets using lead compounds. Science Translational Medicine is offering public access to both the full text and PDF versions of the article. Further details on the Arch2POCM initiative are available on our web site.

30 March 2011- Important International Neurobiology Partnerships. Sage Bionetworks has begun projects to build advanced computational models of neurobiological disease through ongoing partnerships with CHDI Foundation and Takeda Pharmaceutical Company. Analyses and the resulting models will be deposited in the Sage Bionetworks repository and will be valuable public resources available to all interested researchers. 30 March 2011 Press Release.

18 March 2011 - New Oncology Partnership with AstraZeneca. Sage Bionetworks and AstraZeneca have begun an exciting cancer collaboration using advanced computational modeling. The goal is to develop a deeper understanding of cancer to help better match patients with appropriate treatments and might one day lead to new cancer therapeutics. The partnership will combine Sage Bionetworks’ expertise in computer models of disease genetics with AstraZeneca’s extensive knowledge and expertise of oncology including access to data on AstraZeneca’s compounds. “Everyone truly wins in this project,” noted Dr. Stephen Friend, President of Sage Bionetworks. “Sage Bionetworks gets to work with an industry innovator and the resultant computational models will be placed in our public repository and available to all researchers following the completion of the project. Most importantly, we hope patients will gain better drugs.” Further details can be found in the 18 March 2011 Press Release.

2 March 2011 - Sage Bionetworks is hosting two important meetings in April. The 2011 Sage Bionetworks Commons Congress will be on April 15-16 at the UCSF Mission Bay Conference Center in San Francisco. It will feature intensive working sessions of the Communities of Interest that are focused on the strategic and technical challenges of data sharing. Information and program updates can be found on the Congress web site. Immediately following the Congress, Sage Bionetworks and the Structural Genetics Consortium are holding the inaugural meeting of the Arch2POCM initiative. This new project seeks to create a large scale, intellectual property-free environment for community engagement in, and acceleration of, drug discovery. Further details are on the linked public-private partnership page.

27 February 2011 - A video of Stephen Friend's recent talk at TEDx Puget Sound is now available. Entitled,"True Crowd Sourcing of Medicine: Activating all of us" it can be viewed in the embedded video below or at the TEDx YouTube channel.

            

31 January 2011 - "Why Can’t We Just Share all Genomics and Clinical Data?" A Summit on Human Data Interoperability - Join us for an exciting discussion about emerging opportunities to develop tools and infrastructure to collate, share, and mine human genomic/clinical data. Participants from Sage Bionetworks, DARPA/DSO, Stanford University, Columbia University, Creative Commons, Clinical Semantics Group, and UCSF. Monday January 31st, 2011, 11:30 AM – 4:45 PM Lunch Provided Pelton Auditorium, Weintraub Building, Hutchinson Cancer Research Center, Seattle WA - The agenda is available on line.

19 October 2010 - "Opening up Pre-Competitive Collaboration" While many culprits have been implicated in the dire challenges facing pharmaceutical development, a commonly cited solution is improved sharing of early stage research. In February the Institute of Medicine hosted a workshop to explore ‘precompetitive’ models for oncology research.  The participants have published a thoughtful summary of issues and opportunities related to reducing intellectual property hurdles that retard innovation.  Science Translational Medicine is offering special access to the full text of the article as well as to a downloadable PDF.

Congress Videos and Presentations

Videos of the 2010 Sage Bionetworks Commons Congress Presentations are still available on the Congress web site. You can view streaming video from fora.tv or download the video files directly to your computer and view them with a suitably equipped web browser or a flash viewer. PDF copies of most presentations are also available for downloading. The 2011 Congress will be webcast live and presentations and videos will be available on the Congress website shortly after the event.

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News & Discussion Blog

Sage Bionetworks hosts a News and Discussion Forum to provide updates on its activities and as an on-line research community roundtable.  The facility has multiple categories, moderated comments and full search, index and archive capacity for discussing genomic analysis and open access strategies. Sage Bionetworks welcomes inquires from anyone interested in contributing: info@sagebase.org

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Updates, Newsletter and Social Media

Sage Bionetworks provides updates on twitter as well as news on medical research, open science and genetics of interest to our community. Our twitter name is@sagebio and you can also follow us using the #Sagebio hashtag. The annual Sage Bionetworks Commons Congress uses the #SageCon hashtag and has been a rich source of updates and commentary during the April Congresses.

Sage Bionetworks n.b. is a Tumblr. blog where we offer a range of news, videos, links and documents related to our activities and goals. It is designed as an FYI/ICYMI (for your information / in case you missed it) resource for scientists and non-scientists alike hence the n.b (nota bene) suffix. Sage Bionetworks n.b. includes a wide variety of topics such as advanced genomics, open science and health care policy. It provides an opportunity to expand on @sagebio tweets and augments postings and discussions on the Sage Bionetworks Blog.

The Sage Bionetworks Facebook page has updates on Sage Bionetworks, links to interesting news and tabs with blog and twitter updates. You can also sign up for the Sage Bionetworks newsletter which is a concise summary of activities distributed several times a year. Newsletter subscription information is only used to send information on Sage Bionetworks and is never provided to third parties.

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